崔晓宇

姓名：崔晓宇

职称：副研究员

系别：环境科学与生态系

主要研究方向：

1. 污染物无损检测——基于光谱的水探针技术

建立了水探针分析技术，量化揭示了周围环境和溶质对水分子间氢键形成和断裂的调控及机理；解决了复杂水体系难以无损快速定性定量分析的问题，为实现实际样品中微量物质定量分析、结构分析和功能预测提供了新角度。

2. 生态毒理学，污染物暴露评估

水体有害蓝藻大量增殖与其释放的藻毒素共同对水生生态造成了危害。综合性探索了环境因素和种间竞争对蓝藻生长及产毒的协同效应，以揭示蓝藻水华爆发机制以及评估藻毒素生态风险。进一步基于组织病理损伤和免疫调节，研究了蓝藻毒素暴露对斑马鱼的影响以及毒素亲子代传递效应。

3. 生态计量学、化学计量学以及相关数据处理方法开发

开发和发展了多种化学计量学方法，利用学科交叉融合优势，有效地实现了高维数据，复杂重叠信号的分析，揭示了外界条件改变对水溶液影响的机理，对推动水光谱的理论研究和实际应用均具有重要意义，同时为环境大数据分析提供支撑。

电子邮箱：xiaoyucui@tju.edu.cn

通讯地址：天津市津南区雅观路135号北洋园校区环境学院

教育及工作经历（从大学开始填写）：

获奖情况：

学术兼职：

Chemometrics and Intelligent Laboratory Systems，Journal of Pharmaceutical and Biomedical Analysis等期刊审稿人

在研项目（近五年）：

1. 2023年天津大学-福州大学自主创新基金合作项目[经口共暴露时土壤中微塑料对砷的人体健康风险影响及机理的体外试验研究]，主持

2. 第67届博后基金项目[No. 2020M670048（光谱法直接测量大气单颗粒pH值）]，主持

3. 基金委重大研究计划战略项目[No. 91844000（中国大气复合污染的成因与应对机制的基础研究学术交流活动及项目工作计划实施）]，参与

4. “第二次青藏高原科学考察”，任务四“人类活动与生存环境安全”，专题六“高山地方病与高原生理适应”, 2019-2023，参与

5. 国家自然基金项目[No. 21475068（温控近红外光谱及相关化学计量学方法研究）]，参与

6. 国家自然基金项目[No. 21775076（近红外水光谱组学方法与应用研究）]，参与

7. 2022年山东省工业源全口径挥发性有机物分物种排放清单编制项目，参与

主要论文、成果：

1. X.Y. Cui*, Water as a probe for standardization of near-infrared spectra by mutual–individual factor analysis. Molecules 27 (2022) 6069.

2. X.Y. Cui, M.J. Tang, M.J. Wang, T. Zhu*, Water as a probe for pH measurement in individual particles using micro-Raman spectroscopy. Anal. Chim. Acta, 1186 (2021) 339089.

3. X.Y. Cui, Y. Sun, W.S. Cai, X.G. Shao*, Chemometric methods for extracting information from temperature-dependent near-infrared spectra. Sci. China Chem. 62 (2019) 583–591.

4. X.Y. Cui, X.W. Liu, X.M. Yu, W.S. Cai, X.G. Shao*, Water can be a probe for sensing glucose in aqueous solutions by temperature dependent near infrared spectra. Anal. Chim. Acta 957 (2017) 47–54.

5. X.Y. Cui, X.M. Yu, W.S. Cai, X.G. Shao*, Water as a probe for serum–based diagnosis by temperature– dependent near–infrared spectroscopy. Talanta 204 (2019) 359–366.

6. X.G. Shao*, X.Y. Cui, M. Mian, W.S. Cai, High order derivative to investigate the complexity of the near infrared spectra of aqueous solutions. Spectrochim. Acta A 213 (2019) 83–89.

7. X.Y. Cui, J. Zhang, W.S. Cai, X.G. Shao*, Selecting temperature-dependent variables in near-infrared spectra for aquaphotomics. Chemom. Intell. Lab. Syst. 183 (2018) 23–28.

8. X.G. Shao*, X.Y. Cui, X.M. Yu, W.S. Cai, Mutual factor analysis for quantitative analysis by temperature dependent near infrared spectra. Talanta 183 (2018) 142–148.

9. X.Y. Cui, J. Zhang, W.S. Cai, X.G. Shao*, Chemometric algorithms for analyzing high dimensional temperature dependent near infrared spectra. Chemom. Intell. Lab. Syst. 170 (2017) 109–117.

10. X.Y. Cui, W.S. Cai, X.G. Shao*, Glucose induced variation of water structure from temperature dependent near infrared spectra. RSC Adv. 6 (2016) 105729–105736.

11. X.G. Shao*, X.Y. Cui, Y. Liu, Z. Z. Xia, W.S. Cai, Understanding the molecular interaction in solutions by chemometric resolution of near-infrared spectra. ChemistrySelect 2 (2017) 10027–10032.

12. C. Zhang, X.Y. Cui, J. Yang, X.G. Shao, Y.Y. Zhang, D.B. Liu*. Chem. Sci. 11 (2020) 6111–6120.

13. Y. Sun, X.Y. Cui, W.S. Cai, X.G. Shao*, Spectrochim. Acta A, 229 (2020) 117864.

14. L. Han, X.Y. Cui, W.S. Cai, X.G. Shao*, Talanta, 217 (2020) 121036.

15. J. Zhang, X. Y. Cui, W.S. Cai, X.G. Shao*, Sci. China Chem. 62 (2019) 271–279.

16. M. Li, X.Y. Cui, W.S. Cai, X.G. Shao*, Phys. Chem. Chem. Phys. 20 (2018) 20132–20140.

17. 邵学广，马丽，蔡文生，崔晓宇，王利，程丹，朱雪薇，王舒瑜，张进，用于近红外光谱透射光纤探头测量的控温样品池，专利号ZL 2018 2 0096109.3